Daplazole Capsules (60 mg) – 30 Capsules

Composition:

• Active Ingredient: Dexlansoprazole 60 mg

Indications:

• Used for the treatment of conditions related to excessive stomach acid, including:
  • Gastroesophageal reflux disease (GERD)
  • Erosive esophagitis (inflammation of the esophagus caused by acid reflux)
  • Zollinger-Ellison syndrome (a rare condition causing excessive acid production)

Mechanism of Action:

• Dexlansoprazole is a proton pump inhibitor (PPI) that works by irreversibly inhibiting the hydrogen-potassium ATPase enzyme system (the “proton pump”) in the gastric parietal cells. This reduces the production of stomach acid, thereby alleviating symptoms and allowing healing of the esophagus.

Dosage:

• The typical recommended dose is 60 mg once daily, taken at least 30 minutes before a meal.
• Dosage may be adjusted based on individual response and medical guidance.

Side Effects:

• Common Side Effects: Nausea, vomiting, diarrhea, constipation, headache, and abdominal pain.
• Serious Side Effects: Risk of Clostridium difficile infection in the colon, bone fractures, kidney issues, and potential vitamin B12 deficiency with long-term use.

Contraindications:

• Not recommended for individuals with:
  • Known hypersensitivity to dexlansoprazole or any components of the formulation.
  • Use in patients with severe liver impairment should be approached with caution.

Storage:

• Store at room temperature, away from moisture and direct sunlight.

Precautions:

• Regular monitoring may be necessary, especially in long-term therapy.
• Consideration should be given to the potential for drug interactions with other medications.

Patient Counseling:

• Advise taking the medication consistently at the same time each day.
• Encourage patients to follow dietary recommendations to minimize acid reflux.
• Discuss the importance of not abruptly discontinuing the medication without consulting a healthcare provider.

For personalized advice and specific instructions, always consult with a healthcare professional.