Daplazole Capsules (30 mg) – Dexlansoprazole

Composition:

• Active Ingredient: Dexlansoprazole 30 mg per capsule

Indications:

• Used for the treatment of:
  • Gastroesophageal reflux disease (GERD)
  • Erosive esophagitis associated with GERD
  • Maintenance of healing in erosive esophagitis

Mechanism of Action:

• Dexlansoprazole is a proton pump inhibitor (PPI) that works by inhibiting the hydrogen-potassium ATPase enzyme in the gastric parietal cells. This action decreases gastric acid secretion, thereby alleviating symptoms associated with excessive stomach acid.

Dosage:

• The typical recommended dose for adults is 30 mg once daily, taken without regard to meals.
• For some conditions, the dosage may be adjusted based on individual patient response and the specific guidelines provided by a healthcare professional.

Side Effects:

• Common Side Effects: Nausea, vomiting, diarrhea, constipation, flatulence, headache, and abdominal pain.
• Serious Side Effects: Risk of Clostridium difficile infection in the colon, kidney issues, vitamin B12 deficiency with long-term use, and potential for bone fractures.

Contraindications:

• Not recommended for individuals with:
  • Known hypersensitivity to dexlansoprazole or any components of the formulation.
  • Severe hepatic impairment (dose adjustments may be necessary).

Storage:

• Store at room temperature, away from moisture and direct sunlight.

Precautions:

• Regular monitoring may be necessary for long-term users, particularly for vitamin B12 levels and bone health.
• Use with caution in patients with liver disease or those taking medications that may interact with PPIs.

Patient Counseling:

• Advise taking the medication consistently at the same time each day.
• Encourage patients to report any persistent gastrointestinal symptoms or side effects.
• Discuss lifestyle modifications that may help manage GERD symptoms, such as dietary changes and weight management.

For personalized advice and specific recommendations, always consult with a healthcare professional or refer to the product packaging.