Clotrimazole acts against fungi by inhibiting ergosterol synthesis. Inhibition of ergosterol synthesis leads to structural and functional impairment of the fungal cytoplasmic membrane. Clotrimazole has a broad antimycotic spectrum of action in vitro and in vivo, which includes dermatophytes, yeasts and moulds.
USAGE AND SAFETY
Dosage
Clotrimazole
Side Effects
Immune system disorders : Allergic reaction (syncope, hypotension, dyspnoea, urticaria). Gastrointestinal disorders : Abdominal pain . Reproductive system and breast disorders : Genital peeling – (this is a result of the natural exfoliation process of removing damaged vaginal epithelium), pruritus, rash, oedema, erythema, , discomfort, burning, irritation, pelvic pain, vaginal haemorrhage.
Drug Interactions
Oral tacrolimus , sirolimus.
Indication
Infections of the genital region (vaginitis) caused Candida .
When not to Use
Do not use • If you are allergic (hypersensitive) to clotrimazole or any of the other ingredients, including cetostearyl alcohol .
PRECAUTIONS
Precaution
Treatment during the menstrual period should not be performed. The treatment should be completed before the onset of menstruation.
WARNINGS
Warning 1
If symptoms persist for more than 7 days the patient should be evaluated by a medical practitioner.
Warning 2
Recurrent infections may indicate an underlying medical cause. Patient should seek medical advice if symptoms return within 2 months.
Warning 3
It is intended for use by adults and children 12 years of age and older only.
ADDITIONAL INFORMATION
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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