Briax Tablets (20 mg) – Piroxicam Beta-Cyclodextrin

Composition:

• Active Ingredient: Piroxicam beta-cyclodextrin 20 mg per tablet

Indications:

• Used for the management of:
  • Acute and chronic pain conditions, including:
    • Osteoarthritis
    • Rheumatoid arthritis
    • Musculoskeletal disorders
  • Pain relief following surgery or injury.

Mechanism of Action:

• Piroxicam is a nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting the synthesis of prostaglandins, which are mediators of inflammation and pain. The beta-cyclodextrin formulation enhances the solubility and bioavailability of piroxicam, improving its therapeutic efficacy.

Dosage:

• The typical recommended dose is 20 mg taken once daily or as directed by a healthcare provider. For some conditions, the dose may be adjusted based on individual response.

Side Effects:

• Common Side Effects: Nausea, vomiting, diarrhea, stomach pain, headache, and dizziness.
• Serious Side Effects: Risk of gastrointestinal bleeding, kidney toxicity, cardiovascular events, and allergic reactions.

Contraindications:

• Not recommended for individuals with:
  • Known hypersensitivity to piroxicam or any components of the formulation.
  • Active gastrointestinal bleeding, peptic ulcer disease, or severe renal impairment.
  • History of asthma, urticaria, or other allergic-type reactions after taking NSAIDs.

Storage:

• Store at room temperature, away from moisture and direct sunlight.

Precautions:

• Use with caution in patients with cardiovascular disease, hypertension, liver or kidney impairment, and those taking other medications that may increase the risk of side effects.
• Monitor for signs of gastrointestinal bleeding, especially in long-term use.

Patient Counseling:

• Advise patients to take the medication with food to reduce gastrointestinal discomfort.
• Discuss potential side effects, particularly those related to gastrointestinal issues and the importance of reporting any unusual symptoms.
• Encourage adherence to the prescribed dosage and duration of treatment.

For personalized advice and specific recommendations, always consult with a healthcare professional or refer to the product packaging.