Ag-Vono Tablets (20 mg) – 14 Tablets

Composition:

• Active Ingredient: Agomelatine 20 mg

Indications:

• Primarily used for the treatment of major depressive disorder (MDD) in adults.
• It may also be used for anxiety-related symptoms.

Mechanism of Action:

• Agomelatine is a melatonergic antidepressant that acts as a selective agonist of melatonin receptors (MT1 and MT2) and an antagonist of serotonin receptors (5-HT2C). This dual action helps to regulate circadian rhythms and improve mood.

Dosage:

• Typical dosage is one tablet (20 mg) taken once daily, usually at bedtime.
• Dosage may be adjusted based on individual patient response and tolerability.

Side Effects:

• Common Side Effects: Nausea, headache, dizziness, fatigue, and insomnia.
• Serious Side Effects: Liver enzyme elevation, allergic reactions, and possible suicidal thoughts or behavior.

Contraindications:

• Not recommended for patients with:
  • Severe hepatic impairment.
  • Known hypersensitivity to agomelatine or any of its components.

Storage:

• Store at room temperature, protected from moisture and direct sunlight.

Precautions:

• Regular monitoring of liver function is essential due to the potential risk of liver enzyme elevation.
• Patients should be advised about the potential for mood changes and the importance of reporting any worsening symptoms.

Patient Counseling:

• Take the medication consistently at the same time each day, preferably at bedtime.
• Discuss any existing liver conditions or medications with a healthcare provider.
• Advise on recognizing signs of liver issues, such as jaundice or unexplained fatigue.

For personalized guidance and specific recommendations, always consult with a healthcare professional.