Poze Tablets (15 mg) – Pioglitazone HCl

Composition:

• Active Ingredient: Pioglitazone hydrochloride 15 mg per tablet

Indications:

• Used for the management of:
  • Type 2 diabetes mellitus, as an adjunct to diet and exercise.
  • May be used alone or in combination with other antidiabetic medications.

Mechanism of Action:

• Pioglitazone is a thiazolidinedione (TZD) that works by improving insulin sensitivity in muscle and fat tissues. It also reduces glucose production in the liver, helping to lower blood sugar levels.

Dosage:

• The typical starting dose is 15 mg to 30 mg taken once daily. The dose may be adjusted based on the patient’s response, with a maximum dose of 45 mg per day.

Side Effects:

• Common Side Effects: Weight gain, edema (swelling), headache, and nasal congestion.
• Serious Side Effects: Risk of heart failure, liver dysfunction, and bone fractures. There may also be a potential risk for bladder cancer with long-term use.

Contraindications:

• Not recommended for individuals with:
  • Known hypersensitivity to pioglitazone or any components of the formulation.
  • Active bladder cancer or a history of bladder cancer.
  • Severe heart failure or significant hepatic impairment.

Storage:

• Store at room temperature, away from moisture and direct sunlight. Keep out of reach of children.

Precautions:

• Monitor liver function tests periodically during treatment.
• Use with caution in patients with a history of heart failure or fluid retention.
• Patients should be informed about the signs and symptoms of heart failure and to report them promptly.

Patient Counseling:

• Advise patients to take the medication as prescribed, ideally at the same time each day.
• Discuss the importance of adhering to dietary and exercise recommendations alongside medication.
• Encourage regular monitoring of blood glucose levels and to maintain follow-up appointments for diabetes management.

For personalized advice and specific recommendations, always consult with a healthcare professional or refer to the product packaging.