Melfax Tablets 7.5 mg contain Meloxicam, a non-steroidal anti-inflammatory drug (NSAID). It is primarily used to treat pain and inflammation associated with conditions like arthritis. Here’s a detailed overview:

Active Ingredient:

• Meloxicam (7.5 mg): A long-acting NSAID used to reduce pain, inflammation, and fever.

Uses:

1. Osteoarthritis: Meloxicam is often prescribed to relieve pain, swelling, and joint stiffness associated with osteoarthritis (wear and tear of joints).
2. Rheumatoid Arthritis: It is also used to manage the symptoms of rheumatoid arthritis, including inflammation, swelling, and stiffness in the joints.
3. Ankylosing Spondylitis: Meloxicam helps in reducing pain and inflammation associated with ankylosing spondylitis, a chronic condition affecting the spine.

Mechanism of Action:

• Inhibition of Prostaglandins: Meloxicam works by inhibiting the production of prostaglandins, chemicals in the body that cause pain and inflammation. By blocking the cyclooxygenase (COX) enzymes, specifically COX-2, meloxicam reduces the symptoms of pain and inflammation while having less impact on the stomach lining compared to other NSAIDs.

Dosage and Administration:

• Standard Dosage for Adults:
  • Typically, 7.5 mg once daily.
  • In some cases, the dose may be increased to 15 mg daily, depending on the severity of the condition and a doctor’s recommendation.
• Administration:
  • Melfax is taken orally, usually once a day, with or without food. Taking it with food or a glass of milk may help reduce stomach upset.

Side Effects:

Meloxicam, like all NSAIDs, can have side effects, which can range from mild to serious, especially with prolonged use.

• Common side effects:
  • Stomach upset (nausea, vomiting, diarrhea)
  • Indigestion or heartburn
  • Headache
  • Dizziness
• Serious side effects (rare but significant):
  • Stomach ulcers or bleeding
  • High blood pressure
  • Kidney issues (reduced kidney function)
  • Cardiovascular problems (heart attack, stroke, especially with long-term use)
  • Allergic reactions (rash, swelling, or breathing difficulties)

Precautions:

1. Avoid long-term use without medical supervision due to risks of gastrointestinal bleeding, cardiovascular issues, and kidney damage.
2. Patients with heart disease, hypertension, or kidney disease should use meloxicam with caution.
3. Pregnancy: Meloxicam is not recommended during the third trimester of pregnancy, as it can affect the fetal heart and other organs.
4. Allergies to NSAIDs: Patients allergic to other NSAIDs, like aspirin or ibuprofen, should avoid using meloxicam.
5. Interactions: Meloxicam can interact with other medications such as anticoagulants (blood thinners), diuretics, ACE inhibitors, and other NSAIDs, so it’s important to inform your doctor about all medications you’re taking.

Storage:

• Store at room temperature, away from moisture, light, and out of reach of children.

Key Points:

• Meloxicam provides relief from pain and inflammation but should be used carefully due to its potential side effects, especially with prolonged use or in people with preexisting health conditions.
• Always consult with your healthcare provider before starting or adjusting the dosage of Melfax (Meloxicam).

This medication is a helpful option for managing arthritis symptoms but should be used under medical supervision.