Nergab Capsules (50 mg) – 14 Capsules

Composition:

• Active Ingredient: Pregabalin 50 mg

Indications:

• Used for the management of:
  • Neuropathic pain (nerve pain) associated with diabetic peripheral neuropathy or postherpetic neuralgia.
  • Fibromyalgia.
  • Adjunctive therapy for partial-onset seizures in adults.
  • Generalized anxiety disorder (GAD).

Mechanism of Action:

• Pregabalin works by binding to voltage-gated calcium channels in the central nervous system, which reduces the release of excitatory neurotransmitters. This results in decreased neuronal excitability, helping to alleviate pain and anxiety.

Dosage:

• The usual starting dose for neuropathic pain or anxiety is 150 mg per day, which can be increased based on individual response and tolerability, with a maximum dose of 600 mg per day.
• For seizures, dosage may vary based on the specific regimen prescribed by a healthcare provider.

Side Effects:

• Common Side Effects: Dizziness, drowsiness, dry mouth, fatigue, and weight gain.
• Serious Side Effects: Risk of serious allergic reactions, mood changes, or suicidal thoughts. Withdrawal symptoms can occur with abrupt discontinuation.

Contraindications:

• Not recommended for individuals with:
  • Known hypersensitivity to pregabalin or any of its components.

Storage:

• Store at room temperature, away from moisture and direct sunlight.

Precautions:

• Caution is advised when driving or operating machinery until individual tolerance to the medication is determined.
• Monitor for signs of misuse or dependency, especially in patients with a history of substance abuse.

Patient Counseling:

• Advise taking the medication consistently as prescribed, and not to suddenly stop without consulting a healthcare provider.
• Discuss the potential for side effects, especially drowsiness or dizziness.
• Encourage patients to report any mood changes or unusual symptoms to their healthcare provider promptly.

For personalized advice and specific recommendations, it’s essential to consult with a healthcare professional or refer to the product packaging.