Glyzia Met Tablets (50 mg/500 mg)

Composition:

• Active Ingredients:
  • Gliclazide: 50 mg
  • Metformin: 500 mg

Indications:

• Used for the management of type 2 diabetes mellitus, especially in patients who are not adequately controlled with diet and exercise alone.

Mechanism of Action:

• Gliclazide: A sulfonylurea that stimulates insulin secretion from the pancreas and enhances insulin sensitivity in peripheral tissues.
• Metformin: A biguanide that reduces hepatic glucose production, improves insulin sensitivity, and increases peripheral glucose uptake and utilization.

Dosage:

• Typically, the recommended starting dose is one tablet taken once or twice daily, based on the patient’s needs and blood glucose levels.
• Dosage may be adjusted by the healthcare provider according to individual response.

Side Effects:

• Common Side Effects: Nausea, vomiting, diarrhea, abdominal discomfort, and hypoglycemia (especially with gliclazide).
• Serious Side Effects: Lactic acidosis (rare but serious), liver dysfunction, and severe hypoglycemia.

Contraindications:

• Not recommended for patients with:
  • Severe renal impairment
  • Diabetic ketoacidosis
  • Known hypersensitivity to either gliclazide or metformin

Storage:

• Store at room temperature, away from moisture and direct sunlight.

Precautions:

• Regular monitoring of blood glucose levels and kidney function is essential.
• Patients should be informed about signs of hypoglycemia and lactic acidosis.

Patient Counseling:

• Emphasize the importance of adhering to prescribed medications, diet, and exercise.
• Advise on how to recognize and manage low blood sugar levels.

For personalized advice and specific instructions, consult with a healthcare professional.